Cotuit, Massachusetts, offers exceptional fishing opportunities in the heart of Cape Cod, known for its prime estuaries and harbor access. Anglers target striped bass and bluefish migrating through these nutrient-rich waters, particularly during spring and fall runs. Cotuit Harbor Entrance and Cotuit Narrows serve as key hotspots where striped bass congregate near herring runs and deep channels.

The area's diverse ecosystem supports seasonal catches including summer flounder, black seabass, and scup. Shore fishing thrives at locations like Loop Beach and the town beach, where shallow blitzes occur close to shore. Access considerations include resident parking restrictions during peak summer months, though spring and fall provide ideal fishing conditions with fewer limitations.

Deep-sea charters from Cotuit reach nearby Stellwagen Bank for cod, haddock, and halibut, blending cold northern and warm southern fisheries. The harbor's funneling currents create natural fish highways, making it a consistent producer for both bait and lure enthusiasts throughout the seasons.