San Pablo Bay stands as a premier fishing destination in California, renowned for its diverse and abundant fishery. Anglers primarily target trophy Striped bass, the bay's most sought-after species, alongside impressive White sturgeon and hard-fighting Leopard shark. These waters also yield Big skate, Starry flounder, and other species, offering year-round opportunities across varied habitats.

The prime fishing window extends from late November through May, when optimal conditions prevail. Successful techniques include using herring, salmon roe, worms, or lamprey eel as bait, with strategic focus on shell banks, ledges, and drop-offs where fish congregate. Timing excursions during strong minus tides significantly enhances bite rates, while fish finders prove invaluable for locating sturgeon schools.

Regulations require anglers aged 16+ to carry a valid California fishing license, with Striped bass open year-round under a two-fish daily limit. Local charters provide essential knowledge of seasonal patterns and regulation updates, ensuring both novice and experienced anglers maximize their experience in these prolific waters. The bay's accessible location and consistent action cement its status as a must-visit West Coast fishery.